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교수진소개

김건화 프로필 사진
이름
김건화   이메일아이콘
전공
분자세포생물학
연락처
연구실
한국기초과학지원연구원

학력

◈ 2001. 2 : 부산대학교 자연과학부 분자생물학전공 이학사
◈ 2006. 8 : 포항공과대학교 생명과학과 이학박사

주요경력

◈ 2018.9 - 현재 : 충남대학교 분석과학대학원 학연교수
◈ 2017.9 - 현재 : 한국기초과학지원연구원 책임연구원
◈ 2017.9 - 현재 : 과학기술연합대학원대학 전임교원
◈ 2015.9 - 현재 : 고려대학교 생명과학부 겸임교수
◈ 2015.2 - 현재 : 한국기초과학지원연구원 질환표적기능연구팀장

주요연구분야

- 세포신호전달 네트워크
- 중개연구
- 신약개발

주요활동

1. 2015.1 : 보건의료기술진흥 유공자 정부포상 (보건복지부장관 표창)
2. 2015.1 : 한국분자세포생물학회 우수신진연구자상 (블루리본)
3. 2014.8 : 과학기술연합대학원대학교 (UST)우수교원상
4. 2013.12 : 미래창조과학부 기초기술연구회 (현, 국가과학기술연구회)우수신진연구원상
[대표논문]
1) Yun SH†, Park EC†, Lee SY, Lee H, Choi CW, Yi YS, Ro HJ, Lee JC, Jun S, Kim HY, Kim GH* and Kim SI* (2018). Antibiotic treatment modulates protein components of cytotoxic outer membrane vesicles of multidrug-resistant clinical strain, Acinetobacter baumannii DU202. Clinical Proteomics. Accepted (Co-author, IF: 3.274)
2) Park EC†, Lim JS †, Kim SI†, Lee SY, Tak YK, Choi CW, Yun SH, Park J, Lee M, Chung HK, Kim KS, Na YG, Shin JH* and Kim GH* (2018). Proteomic analysis of urothelium of rats with detrusor overactivity induced by bladder outlet obstruction. Molecular & Cellular Proteomics. 17(5):948-960 (Co-corresponding author, IF:6.540)
3) Park EC†, Lee SY†, Yun SH, Choi CW, Lee H, Song HS, Jun S, Kim GH, Lee CS* and Kim SI* (2018). Clinical proteomic analysis of Scrub typhus infection. Clinical Proteomics. 14;15:6 (Co-author, IF: 3.274)
4) Lee SY†, Park EC†, Yun SH, Choi CW, Park EC, Song HS, Lee H, Shin J, Chung C, Moon JY, Lee JC, Kim GH* and Kim SI* (2018). Genomic characterization of extensively drug-resistant Acinetobacter baumannii strain, KAB03 belonging to ST451 from Korea. Infection, Genetics and Evolution. 25;65:150-158 (Co-corresponding author, IF: 2.885)
5) Choi CW†, Park EC†, Yun SH, Lee SY, Kim SI* and Kim GH* (2017). Potential Use of Streptococcus pneumoniae Extracellular Membrane Vesicles for Vaccines. Journal of Immunology Research. 2017: 7931982 (Co-corresponding author, IF: 3.276)
6) Yun SH, Lee SY, Choi CW, Lee H, Ro HJ, Jun S, Kwon KK, Kim SJ, Kim GH and Kim SI (2017). Proteomic characterization of the outer membrane vesicle of the halophilic marine bacterium Novosphingobium pentaromativorans US6-1. Journal of Microbiology. 55(1):56-62 (Co-author, IF: 1.924)
7) Lee SY†, Kim GH†, Yun SH, Choi CW, Yi YS, Kim J, Chung YH, Park EC and Kim SI. Proteogenomic characterization of monocyclic aromatic hydrocarbon degradation pathways in the aniline-degrading bacterium Burkholderia sp. K24. PLoS One. 28;11(4):e0154233 (Co-first author, IF: 2.806)
8) Lee H†, Lee SJ†, Kim GH, Yeo I, and Han JK (2016 Mar). PLD1 regulates Xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation. Developmental Biology. 411(1):38-49 (Second author, IF: 2.944)
9) Shin JH†, Chun KS†, Na YG, Song KH, Lim JS* and Kim GH* (2015). Allopurinol Protects Against Ischemia/Reperfusion-induced Injury in Rat Urinary Bladders. Oxidative Medicine and Cellular Longevity. 2015:906787 (Co-corresponding author, IF: 4.593)
10) Choi CW†, Park EC†, Yun SH, Lee SY, Lee YG, Hong Y, Park KR, Kim SH, Kim GH, and Kim SI (2014). Proteomic characterization of the outer membrane vesicle of Pseudomonas putida KT2440. Journal of Proteome research. 13(10):4298-309 (Co-author, IF: 4.268)
11) Park EC†, Kim SI†, Hong Y, Hwang JW, Cho GS, Cha HN, Han JK, Yun CH, Park SY, Jang IS, Lee ZW, Choi JS*, Kim S* and Kim GH* (2014 Oct). Inhibition of CYP4A Reduces Hepatic Endoplasmic Reticulum Stress and Features of Diabetes in Mice. Gastroenterology. 147(4):860-9 (Co-corresponding author, IF: 18.392)
12) Park SY, Lee HU, Kim GH, Park EC, Lee YC, Han SH, Choi S, Heo NS, Kim DL, Huh YS, and Lee J (2014 Sep). Wound healing potential of antibacterial microneedles loaded with green tea. Materials Science & Engineering C-Materials for Biological Applications. 1(42):757-62 (Third author, IF: 4.164)
13) Kim GH, Choi CW, Park EC, Lee SY and Kim SI (2014 May). Isolation and proteomic characterization of bacterial Extracellular membrane vesicles. Current Protein & Peptide Science: Invited Review. 15(7):719-31. (First author, IF: 2.576)
14) Lee SY, Yun SH, Lee YG, Choi CW, Leem SH, Park EC, Kim GH, Lee JC and Kim SI (2014 Jun). Proteogenomic characterisation of antimicrobial resistance in extensively drug-resistant Acinetobacter baumannii DU202. Journal of Antimicrobial Chemotherapy. 69(6):1483-91 (Co-author, IF: 5.071)
15) Shin JH†, Kim GH†, Son KH, Na YG, Sul CK and Lim JS (2014 Jan). Protective effect of N-acetylcysteine on Ischemia/Reperfusion Injury in Rat Urinary Bladder. Cell Biochemistry and Function. 32(1):24-30. (Co-first author, IF: 2.214)
16) Choi CW, An HY, Lee YJ, Lee YG, Yun SH, Park EC, Hong Y, Kim GH, Park JE, Baek SJ, Kim HS and Kim SI (2013 Oct). Characterization of Streptococcus pneumoniae N-acetylglucosamine-6-phosphate deacetylase as a novel diagnostic marker. Journal of Microbiology. 51 (5): 659-64 (Co-author, IF: 1.924)
17) Shin EY, Park EC, Hong Y and Kim GH* (2013 Jul). Protein Kinases Involved in the Regulation of Wnt/β-catenin Signaling. Journal of Life Science: Invited Review. 23 (7): 947-954 (Corresponding author)
18) Kim GH†, Park EC†, Lee H, Na HJ, Choi SC* and Han JK (2013 May). β-arrestin1 mediates non-canonical Wnt pathway to regulate convergent extension movements. Biochemical and biophysical research communications. 435 (2): 182-187 (Co-first author, IF: 2.466)
19) Park EC†, Kim G†, Jung J, Wang KM, Lee S, Jeon SS, Lee ZW, Kim SI, Kim S, Oh YT, Shin JH, Jang HS, Choi BO* and Kim GH* (2013 May). Differential expression of microRNAs in patients with glioblastoma after concomitant chemoradiotherapy. OMICS: A Journal of Integrative Biology. 17 (5): 259-268 (Co-corresponding author, IF: 2.723)
20) Kim GH†, Park EC†, Yun SH, Hong Y, Lee DG, Jung J, Kim YH, Lee KB, Jang KS, Lee ZW, Chung YH, Choi JS, Cheong C, Kim S* and Kim SI* (2013 Apr). Proteomic and bioinformatic analysis of membrane proteome in type 2 diabetic mouse liver. Proteomics. 13 (7): 1164-1179 (Co-first author, IF: 4.041)
21) Hong Y†, Park EC†, Shin EY, Kwon SO, Oh YT, Choi BO, Kim G* and Kim GH* (2013 Apr). Proteomic and bioinformatic analysis of recurrent anaplastic oligodendroglioma. Journal of Analytical Science & Technology. 4: 6 (Co-corresponding author)
22) Park EC†, Kim GH†, Yun SH, Lim HL, Hong Y, Kwon SO, Kwon J, Chung YH* and Kim SI* (2012 Dec). Analysis of the endoplasmic reticulum subproteome in the livers of type 2 diabetic mice. International Journal of Molecular Sciences, Special Issue: Advances in Proteomics Research. 13 (12): 17230-17243 (Co-first author, IF: 3.226)
23) Park EC†, Lee H†, Hong Y, Kim MJ, Lee ZW, Kim SI, Kim S, Kim GH* and Han JK* (2012 May). Analysis of the expression of microtubule plus-end tracking proteins (+TIPs) during Xenopus laevis embryogenesis. Gene Expression Patterns. 12 (5-6): 204-212 (Co-corresponding author, IF: 1.158)
24) Hwang JM, Lee KB, Choi JS, Rho J, Kim GH, Kim SI, Kim S, and Lee ZW (2011 Dec). Novel technology for protein-protein interaction-based targeted drug discovery. Journal of Analytical Science & Technology. 2: 61 -65 (Co-author)
25) Kim G †, Park EC †, Ryu CH, Jeon SS, Kim SI, Jang HS, Kim GH* and Choi BO* (2011 Nov). MicroRNA expression profiling in recurrent anaplastic oligodendroglioma treated with postoperative radiotherapy. Journal of Analytical Science & Technology. 2 (2): 97-104 (Co-corresponding author)
26) Park EC, Cho GS, Kim GH, Choi SC, and Han JK (2011 Feb). The Involvement of Eph-Ephrin Signaling in Tissue Separation and Convergence during Xenopus Gastrulation Movements. Developmental Biology. 350(2):441-450 (Co-author, IF: 2.944)
27) Lee KB, Hwang JM, Choi I, Rho J, Choi JS, Kim GH, Kim SI, Kim S, and Lee ZW (2011 Feb). Direct Monitoring of Protein-Protein Interaction Inhibition in Cells by Translocation of PKC Fusion Protein. Angewandte Chemie-International Edition. 50(6):1314-1317 (Co-author, IF: 11.994)
28) Kim YH, Kim GH, Shin JH, Kim KS, and Lim JS (2010 Dec). Effect of Korean Red Ginseng on Testicular Tissue Injury after Torsion and Detorsion. Korean Journal of Urology. 51:794-799 (Second author)
29) Park EC, Kim M, Hur JY, Lee ZW, Han JK, and Kim GH (2010 Nov). Identification of binding proteins in Xenopus laevis by MALDI-TOF/TOF mass spectrometry. Journal of Analytical Science & Technology. 1 (2): 152 -158 (Corresponding author)
30) Kim GH, Her JH, and Han JK (2008 Sep). Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus convergent extension movements. Journal of Cell Biology. 182(6): 1073-1082 (First author, IF: 7.955)
31) Choi SC*, Kim GH*, Lee SJ, Park EJ, Yeo CH, and Han JK (2008 July) (* These authors contributed equally to this work). Regulation of Activin/Nodal Signaling by Rap2-Directed Receptor Trafficking. Developmental Cell. 15(1): 49–61 (Co-first author, IF: 9.174)
- Commented in Gonzalez-Gaitan M (2008 Aug) The garden of forking paths: recycling, signaling, and degradation. Developmental cell, 15(2):172-4
32) Kim GH and Han JK (2007 May). Essential role for β-arrestin2 in the regulation of Xenopus convergent extension movements. The EMBO Journal. 26(10): 2513-2526 (First author, IF: 9.792)
- Featured in This Issue in the EMBO Journal
- Is one of the 10 most-read/downloaded articles in the EMBO Journal during May 2007
33) Park EJ, Kim GH, Choi SC and Han JK (2006 Apr). Role of PKA as a negative regulator of PCP signaling pathway during Xenopus gastrulation movements. Developmental Biology. 292(2):344-357 (Second author, IF: 2.944)
34) Kim GH, Park EJ, Kong YY, and Han JK (2006 Apr). Novel function of POSH, a JNK scaffold, as an E3 ubiquitin ligase for the Hrs stability on early endosomes. Cellular signalling. 18(4):553-563 (First author, IF: 3.937)
35) Kim GH, Park EJ, and Han JK (2005 Oct). The assembly of POSH-JNK regulates Xenopus anterior neural development. Developmental Biology 286(1):256-269 (First author, IF: 2.944)
36) Kim GH and Han JK (2005 Apr). JNK and ROKα function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements. Developmental Dynamics. 232(4):958-968 (First author, IF: 2.004)