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교수진소개

김영환 프로필 사진
이름
김영환   이메일아이콘
전공
지질체 분석 및 질량분석 이미징 연구
연락처
연구실
한국기초과학지원연구원

학력

◈ 1984. 3. 2 ~ 1988. 2. 28 : 서울대학교 화학과 이학사
◈ 1989. 3. 2 ~ 1991. 2. 28 : 서울대학교 대학원 화학과(물리화학) 이학석사
◈ 1995. 3. 2 ~ 1999. 8. 31 : 서울대학교 대학원 화학과(생분석화학) 이학박사

주요경력

[경력]
◈ 1991. 1. 1. ~ 현재 : 한국기초과학지원연구원, 책임연구원
◈ 2001. 10. 2. ~ 2001. 10. 1 : Complex Carbohydrate Research Center, Univ. of Georgia, USA , 박사후연수원
◈ 2004. 1. ~ 2013. 12 : 한국질량분석학회 이사
◈ 2012. 1. ~ 2012. 12 : 대한화학회 산학연 협력 실무이사
◈ 2013. 1. ~ 2013. 12 : 대한화학회 분석화학분과 총무간사
◈ 2004. 9. 1. ~ 현재 : 과학기술연합대학원대학교, 교수
◈ 2010. 3. 1. ~ 현재 : 충남대학교 분석과학기술대학원 학연교수

[수상실적]
◈ 2006. 1. 6 : 한국기초과학지원연구원 논문대상
◈ 2008. 8. 23 : 교육과학기술부장관 표창
◈ 2010. 6. 23 : 대전시 이달의 과학기술자상 수상
◈ 2011. 1. 3 : 한국기초과학지원연구원 논문 우수상
◈ 2011. 12. 1 : 한국기초과학지원연구원 영년직연구원 임명
◈ 2014. 10. 6 : 대한화학회 분석화학 학술상 수상

주요연구분야

- 질량분석을 통한 유기물질, 생체고분자 물질(단백질, 지질, 당)의 구조분석
- 프로테옴(proteome), 지질체(lipidome) 그리고 glycome 분석

주요활동

[주요논문] (2011년 이후)
1.	K.-S. Shin*, H.-S. Park, Y. Kim, I.-B. Heo, Y. H. Kim*, J.-H. Yu*, “Aspergillus fumigatus spore proteomics and genetics reveal that VeA represses DefA-mediated DNA damage response”, Journal of Proteomics, 148, 26-35 (2016)
2.	T. Acter, D. Kim, A. Ahmed, J. M. Jin, U. Yim, W. Shim, Y. H. Kim*, S. Kim*, “Optimization and Application of Atmospheric-Pressure Chemical and Photoionization Hydrogen–Deuterium Exchange Mass Spectrometry for Speciation of Oxygen-containing Compounds”, Analytical and Bioanalytical Chemistry, 408(12), 3281-3293 (2016)
3.	D. Kim†, J. M. Jin†, Y. Cho, E.-H. Kim, H.-K. Cheong, Y. H. Kim*, and S. Kim*, “Combination of Ring Type HPLC Separation, Ultrahigh -resolution Mass Spectrometry and High Field NMR for Comprehensive Characterization of Crude Oil Compositions”, Fuel, 157, 48-55 (2015).
4.	H.-M. Park†, M. P. Hwang†, Y.-W. Kim, K.-J. Kim, J. M. Jin, Y. H. Kim, Y.-H. Yang, B.-G. Kim, K. H. Lee*, Y.-G. Kim*, “Mass spectrometry-based N-linked glycomic profiling as a means for tracking pancreatic cancer metastasis”, Carbohydrate Research, 413, 5-11 (2015)
5.	K.-S. Shin*, Y. H. Kim and J.-H. Yu*, “Proteomic analyses reveal the key roles of BrlA and AbaA in biogenesis of gliotoxin in Aspergillus fumigatus”, Biochemical and Biophysical Research Communications, 463(3), 428-433 (2015)
6.	K.-J. Kim†, H.-M. Park†, Y.-W Kim, J. M. Jin, Y.-H. Yang, J. K. Lee, J. Chung, S.-G. Lee, A. Saghatelian, Y. H. Kim* and Y.-G. Kim*, “Stable isotopic labeling-based quantitative targeted glycomics (i-QTaG)”, Biotechnology Progress, 31(3), 840-848 (2015).
7.	H.-M. Park, Y.-W. Kim, K.-J. Kim, Y. J. Kim, Y.-H. Yang, J. M. Jin, Y. H. Kim, B.-G. Kim, H. Shin*, Y.-G. Kim*,“Comparative N-linked glycan analysis of wild-type and α-1,3-galactosyltransferase gene knock-out pig fibroblasts using mass spectrometry approaches”, Molecules and Cells, 38(1), 65-74 (2015)
8.	J. Kang†, H.-M. Park†, I.-S. Park, Y.-W. Kim, Y. H. Kim, S. Varghese, Y.-G. Kim* and S.-H. Kim*, “Control of mesenchymal stem cell phenotype and differentiation by an artificial biofunctional adhesion matrix”, European Cell & Materials, 28, 387-403 (2014)
9.	Y. J. Cho, M. Witt,J. M. Jin, Y. H. Kim, N.-S. Nho and S. Kim*, “Evaluation of Laser Desorption Ionization Coupled to Fourier Transform Ion Cyclotron Resonance Mass Spectrometry to Study Metalloporphyrin Complexes”, Energy & Fuels, 28(11), 6699-6706 (2014)
10.	I. C. Kim†, G. Bang†, J. H. Lee, K. P. Kim, Y. H. Kim*, H. K. Kim*, and J.-S. Chang*, “Low C24-OH and C22-OH sulfatides in human renal cell carcinoma”, Journal of Mass Spectrometry, 49(5), 409-416 (2014)
11.	S. Y. Kwon†, S. H. Choi†, Y. S. Park, D. Y. Park, Y. I. Park, I. Hwang, M. H. Ryu, C. H. Kwon, J. H. Lee, G. Bang, K. P. Kim, Y. H. Kim, H. K. Kim*, “Lipid MALDI MS profiles of gastric cancer”, The Open Proteomics, 7, 1-4 (2014)
12.	J. M. Jin, J. Yoo, S. Y. Jang, K. Cho and Y. H. Kim*, “Characterization of N-linked glycan structures using normal-phase capillary LC-MALDI tandem mass spectrometry”, Bulletin of the Korean Chemical Society, 35(3), 955-957 (2014)
13.	A. Islam, Y. Cho, U. H. Yim, W. J. Shim, Y. H. Kim, and S. Kim*, “The comparison of weathered oil spills at two stages and photo-degraded oils at one stage at the molecular level by a combination of SARA fractionation and FT-ICR MS”, Journal of Hazardous Materials, 263, 404-411 (2013)
14.	E. Cho, M. Ahn, Y. H. Kim, J. Kim* and S. Kim*, “Protons are one of the limiting factors in determining sensitivity of nano surface-assisted (+)-mode LDI MS analyses”, Journal of American Society for Mass Spectrometry, 24(10), 1489-1492 (2013)
15.	J. S. Yoo†, T. S. Park†, G. Bang, C. Lee, J.-R. Rho and Y. H. Kim*, “High-energy collision-induced dissociation of [M+Na]+ ions desorbed by fast atom bombardment of ceramides isolated from the starfish Distolasterias nipon", Journal of Mass Spectrometry, 48(2), 164-171 (2013).
16.	S. R. Shanta†, T. Y. Kim †, J.-H. Hong, J. H. Lee, C. Y. Shin, K.-H. Kim, Y. H. Kim, S. K. Kim, and K. P. Kim*, “A new combination MALDI matrix for small molecule analysis: application to imaging mass spectrometry for drugs and metabolites”, Analyst, 137(24), 5757-5762 (2012).
17.	Y. Cho, M. Witt, Y. H. Kim, and S. Kim*, “Characterization of crude oils at the molecular level by use of laser desorption ionization Fourier-transform ion cyclotron resonance mass spectrometry”, Analytical Chemistry, 84(20), 8587-8594 (2012).
18.	S. Kang, H. Maeng, B. G. Kim, G. M. Qing, Y. P. Choi, H. Y. Kim, P. S. Kim, Y. Kim, Y. H. Kim, Y. D. Choi and N. H. Cho*, “In-situ identification and localization of IGHA2 in the breast tumor microenvironment by mass spectrometry” Journal of Proteome Research, 11(9), 4567-4574 (2012).
19.	J. M. Jin, S. Choi, Y. H. Kim, M. H. Choi, J. Kim* and S. Kim*, “Evaluation of nanoporous gold with controlled surface structures for laser desorption ionization (LDI) analysis: surface area vs. LDI signal intensity”, Journal of American Society for Mass Spectrometry, 23(9), 1450-1453 (2012).
20.	S. Kang, A. Lee, Y. S. Park, S. C. Lee, S. Y. Park, S. Y. Han, G. P. Kim, Y. H. Kim*, C. W. Yoo* and H. K. Kim*, “Alternation in lipid and protein profiles of ovarian cancer: similarity to breast cancer”, International Journal of Gynecological Cancer, 21(9), 1566-1572 (2011).
21.	Y. S. Park, C. W. Yoo, S. C. Lee, S. J. Park, J. H. Oh, B. C. Yoo, S. S. Paik, K. G. Lee, S. Y. Jin, S.-C. Kim, K. P. Kim, Y. H. Kim*, D. H. Choi* and H. K. Kim*, “Lipid profiles for intrahepatic cholangiocarcinoma identified using matrix-assisted laser desorption/ionization mass spectrometry” Clinica Chimica Acta, 412(21-22), 1978-1982 (2011).
22.	Y. Cho, Y. H. Kim and S. Kim*, “Planar Limit-assisted Structural Interpretation of SARA Fractionated Crude Oil Compounds Observed by FT-ICR MS” Analytical Chemistry, 83(15), 6068-6073 (2011).
23.	S. R. Shanta, Y. Kim, Y. H. Kim, and K. P. Kim*, “Application of MALDI tissue imaging of Drugs and Metabolites: a new frontier for molecular histology” Biomolecules and Therapeutics, 19(2), 149-154 (2011)
24.	J. Y. Kim, Y.-G. Kim, Y. K. Han, H. S. Choi, Y. H. Kim* and G. M. Lee*, “Proteomic Understanding of Intracellular Responses of Recombinant Chinese Hamster Ovary Cells Cultivated in Serum-Free Medium Supplemented with Hydrolysates”, Applied Microbiology and Biotechnology, 89(6), 1917-1928 (2011)
25.	S. R. Shanta1, L.-H. Zhou1, Y. S. Park, Y. H. Kim, Y. Kim, and K. P. Kim*, “A binary matrix for MALDI imaging mass spectrometry of phospholipids in both ion modes”, Analytical Chemistry, 83(4), 1252-1259 (2011)
26.	T. Park, Y. S. Park, J.-R. Rho and Y. H. Kim*, “Structural determination of cerebrosides isolated from Asterias amurensis starfish eggs using high-energy collision-induced dissociation of sodium-adducted molecules", Rapid Communications in Mass Spectrometry, 25(5), 572-578 (2011)